Company Filing History:
Years Active: 2003-2017
Title: **Inventor Douglas Richman: Pioneering Methods for Viral Inhibition**
Introduction
Douglas Richman, a distinguished inventor based in La Jolla, California, has made significant contributions to the field of virology through his innovative work. With a total of five patents, Richman's research focuses on evaluating viral receptor usage and developing inhibitors that prevent virus entry into host cells. His latest inventions showcase advanced methodologies aimed at combating viral infections, reinforcing his reputation as a leading figure in biomedical research.
Latest Patents
Douglas Richman holds several patents, with his latest innovations including methods for evaluating viral receptor/co-receptor usage and inhibitors of virus entry utilizing recombinant virus assays. The first patent provides a sophisticated approach to identifying whether a compound inhibits viral entry into a cell. This method involves obtaining nucleic acid from a patient's viral envelope protein, co-transfecting it into a first cell alongside a viral expression vector lacking the envelope protein encoding, and subsequently measuring the viral signal produced in the presence of the compound.
Another significant patent details a method for determining the presence of antibodies that block viral infections. This process similarly involves obtaining nucleic acid from an infected patient, co-transfecting it into a cell with a viral expression vector, and then assessing the infectivity of the produced viral particles by measuring the signal in target cells, both with and without the compound in question.
Career Highlights
Throughout his career, Douglas Richman has worked with notable organizations, including Monogram Biosciences, Inc. His experience in the industry has allowed him to deepen his understanding of viral mechanisms and contribute to the development of innovative therapeutic strategies. Richman's impressive portfolio of patents not only highlights his inventive capabilities but also reflects his dedication to advancing the science of virology.
Collaborations
Richman has collaborated with esteemed colleagues such as Mary T. Wrin and Susan Little, further enhancing the impact of his research. These collaborations have fostered a multidisciplinary approach to tackling viral infections, combining various expertise and perspectives to yield comprehensive solutions in the field.
Conclusion
Douglas Richman stands out as an influential inventor whose work addresses critical challenges in viral infections. His latest patents underscore a commitment to developing effective methodologies for viral inhibition. Through collaboration and innovation, Richman's contributions have the potential to lead to significant advancements in the treatment of viral diseases, affirming his role as a key player in the biomedical research community.