The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2017
Filed:
Oct. 29, 2015
Monogram Biosciences, Inc., South San Francisco, CA (US);
Douglas Richman, La Jolla, CA (US);
Mary T Wrin, Fremont, CA (US);
Susan Little, San Diego, CA (US);
Christos J. Petropoulos, Half Moon Bay, CA (US);
Neil T. Parkin, Belmont, CA (US);
Jeannette Whitcomb, San Mateo, CA (US);
Wei Huang, Foster City, CA (US);
Monogram Biosciences, Inc., South San Francisco, CA (US);
Abstract
Provided are methods for identifying whether a compound inhibits entry of a virus into a cell. The method may include obtaining nucleic acid encoding a viral envelope protein from a patient infected by the virus and co-transfecting it into a first cell along with a viral expression vector which lacks a nucleic acid encoding the envelope protein. The method may further include contacting the viral particles produced by the first cell with a second cell to which the virus binds in the absence and presence of the compound and measuring the amount of signal produced by the second cell.