Company Filing History:
Years Active: 1998-2008
Title: Innovations of Dorothy L Reimer
Introduction
Dorothy L Reimer is a prominent inventor based in Vancouver, Canada. She has made significant contributions to the field of gene transfer technology, holding a total of 6 patents. Her work focuses on developing lipid-nucleic acid particles that enhance the delivery of genetic material for therapeutic purposes.
Latest Patents
One of her latest patents is titled "Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer." This patent describes novel lipid-nucleic acid particulate complexes that are useful for both in vitro and in vivo gene transfer. The particles can be formed using either detergent dialysis methods or methods that utilize organic solvents. Upon removal of a solubilizing component, the lipid-nucleic acid complexes form particles that are serum-stable and protected from degradation. These particles have access to extravascular sites and target cell populations, making them suitable for the therapeutic delivery of nucleic acids. Another significant patent is "Method of preventing aggregation of a lipid:nucleic acid complex." This invention prevents particle aggregation by incorporating a non-cationic lipid into lipid:nucleic acid complex particles that contain a cationic lipid and a nucleic acid polymer. The non-cationic lipid used is a polyethylene glycol-based polymer.
Career Highlights
Throughout her career, Dorothy has worked with notable organizations such as Inex Pharmaceuticals Corporation and the University of British Columbia. Her innovative research has paved the way for advancements in gene therapy and molecular medicine.
Collaborations
Dorothy has collaborated with esteemed colleagues, including Marcel B Bally and Yuan-Peng Zhang. Their joint efforts have contributed to the development of groundbreaking technologies in the field.
Conclusion
Dorothy L Reimer's contributions to the field of gene transfer technology are invaluable. Her innovative patents and collaborations highlight her dedication to advancing medical science.
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