Gaithersburg, MD, United States of America

Dorothea H Scandella


Average Co-Inventor Count = 3.0

ph-index = 2

Forward Citations = 37(Granted Patents)


Company Filing History:


Years Active: 1990-1992

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3 patents (USPTO):Explore Patents

Title: Discovering the Innovations of Dorothea H. Scandella

Introduction

Dorothea H. Scandella is a prominent inventor based in Gaithersburg, MD, who has made significant contributions to the field of biotechnology. With a portfolio of three patents, her work primarily focuses on gene regulation and coagulation factors, showcasing her expertise and dedication to advancing medical science.

Latest Patents

One of her notable inventions is the "Hybrid gene regulatory region operable in E. coli." This patent presents a novel hybrid regulatory region designed to direct and regulate the transcription and translation of gene sequences positioned downstream. The innovation incorporates the promoter sequence of the phage lambda P.sub.R promoter-operator region, fused to the operator sequence of phage lambda P.sub.L promoter-operator region, providing a significant advancement in genetic engineering.

Another significant patent involves "Recombinant Factor VIIIC fragments." This invention details new fragments of the Factor VIII procoagulant protein, which are essential for treating patients who have developed antibodies inhibiting Factor VIII. Notably, these fragments exhibit Mr values of 88,000 d or 49,000 d and extend from specific amino acid residues. Such advancements hold great potential for improving therapeutic options in hemophilia treatment.

Career Highlights

Throughout her career, Dorothea H. Scandella has had the opportunity to work with prestigious institutions, including the Scripps Clinic and Research Foundation, as well as Rorer Biotechnology Inc. Her experience at these establishments has allowed her to hone her research capabilities while contributing to various innovative projects.

Collaborations

Scandella has collaborated with several esteemed colleagues, including William N. Drohan and Theodore S. Zimmerman. These collaborations have enriched her research, leading to advancements in biotechnology and enhancing the development of her patented inventions.

Conclusion

Dorothea H. Scandella exemplifies dedication and innovation in the field of biotechnology. Her patents not only represent her contributions but also pave the way for further research and advancements in medical treatment. As her career continues to evolve, the impact of her work on the scientific community and patient care remains significant.

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