Location History:
- Mountain View, CA (US) (2003 - 2006)
- Cupertino, CA (US) (1999 - 2011)
Company Filing History:
7 out of 12 
4 out of 26 
3 out of 12 Years Active: 1999-2011
Title: The Innovative Contributions of Dongxu Sun
Introduction
Dongxu Sun is a prominent inventor based in Cupertino, California, known for his significant contributions to the field of antimicrobial agents. With a total of 16 patents to his name, he has made remarkable strides in developing solutions to combat drug-resistant bacterial infections.
Latest Patents
Among his latest patents are two notable inventions. The first is focused on bacterial efflux pump inhibitors and methods of treating bacterial infections. This invention specifically addresses the need for Efflux Pump Inhibitor (EPI) compounds that can be co-administered with antimicrobial agents to treat infections caused by drug-resistant pathogens. The EPI compounds are designed as soft drugs, which exhibit a reduced propensity for tissue accumulation. The invention encompasses novel compounds that serve as efflux pump inhibitors, along with compositions and devices that incorporate these inhibitors for therapeutic use.
The second patent enhances the potency of tigecycline using efflux pump inhibitors. This invention reveals that EPI compounds can be co-administered with antimicrobial agents to effectively treat infections caused by drug-resistant pathogens. The EPIs not only increase the potency of tigecycline but also decrease bacterial resistance and enhance the killing effectiveness of the drug. Additionally, methods of treatment and pharmaceutical compositions for co-administering tigecycline with an EPI are disclosed.
Career Highlights
Dongxu Sun has worked with several notable companies in the pharmaceutical industry, including Iconix Pharmaceuticals, Inc. and Microcide Pharmaceuticals, Inc. His work in these organizations has contributed to the advancement of antimicrobial research and the development of innovative treatment methods.
Collaborations
Some of his coworkers include Bret Benton and Molly B Schmid, who have collaborated with him on various projects throughout his career.
Conclusion
Dongxu Sun's innovative work in the field of antimicrobial agents has led to significant advancements in treating drug-resistant bacterial infections. His contributions through patents and collaborations highlight his commitment to improving healthcare solutions.