Houston, TX, United States of America

Dong-Fang Yu

USPTO Granted Patents = 24 


 

Average Co-Inventor Count = 4.0

ph-index = 12

Forward Citations = 791(Granted Patents)


Company Filing History:


Years Active: 1999-2017

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24 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Dong-Fang Yu in Glycopeptide Research

Introduction

Dong-Fang Yu, an esteemed inventor located in Houston, TX, has made significant contributions to the field of glycopeptides, holding an impressive total of 24 patents. His work primarily focuses on the synthesis and applications of glycopeptide compositions, showcasing his commitment to innovating therapeutic and diagnostic methods.

Latest Patents

Among his notable inventions, Yu has developed glycopeptide compositions that feature glycosides covalently bound to peptides through amide bonds. These innovative glycopeptides can be conjugated with various diagnostic or therapeutic agents, including radionuclides, which are beneficial for imaging and treatment purposes. Notably, specific embodiments involve glycopeptides composed of chitosan linked to poly(amino acids) like poly(glutamic acid) or poly(aspartic acid). The potential applications of these compositions encompass cancer treatment, rheumatoid arthritis therapy, and other critical medical interventions.

Another significant patent by Yu focuses on the efficient synthesis of ethylenedicysteine-sugar conjugates. He presents novel methods for producing these conjugates in high purity, using starting materials like thiazolidine carboxylic acid. The resulting conjugates are instrumental in diagnostic imaging for tumors and diagnosing conditions such as myocardial ischemia, highlighting their dual therapeutic and diagnostic capabilities.

Career Highlights

Dong-Fang Yu's career includes influential roles at the University of Texas System and Pg-txl Company, L.P. His innovative research and expertise in glycopeptide synthesis have positioned him as a leader in his field, contributing to advancements in medicine through his patented inventions.

Collaborations

Throughout his career, Yu has collaborated with notable individuals such as David J. Yang and Chun Li. These partnerships have enriched his research endeavors, fostering an environment of innovation and discovery.

Conclusion

In summary, Dong-Fang Yu's contributions to glycopeptide research are characterized by his extensive patent portfolio and collaborative efforts. His inventions continue to pave the way for innovative therapeutic and diagnostic applications, reflecting his pivotal role in advancing medical science.

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