The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2017
Filed:
Mar. 26, 2013
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
David J. Yang, Sugar Land, TX (US);
Dong-Fang Yu, Houston, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); A61K 49/00 (2006.01); A61K 51/04 (2006.01); A61K 31/70 (2006.01); A61K 45/06 (2006.01); A61K 31/7048 (2006.01); C07H 13/04 (2006.01); C07H 13/10 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0004 (2013.01); A61K 31/70 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01); A61K 49/0002 (2013.01); A61K 51/0491 (2013.01); C07D 417/12 (2013.01); C07H 13/04 (2013.01); C07H 13/10 (2013.01);
Abstract
Novel methods of synthesis of ethylenedicysteine-sugar conjugates and therapeutic and diagnostic applications of such conjugates are disclosed. Methods of synthesizing these conjugates in high purity are also presented as using starting materials such as thiazolidine carboxylic acid. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these conjugates prepared herein, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.