Company Filing History:
Years Active: 2017
Title: Innovations in Cancer Research by Donald William Parsons
Introduction
Donald William Parsons is a notable inventor based in Ellicott City, MD (US). He has made significant contributions to the field of cancer research, particularly through his work on protein kinases and their role in colorectal cancers. His innovative approach has led to advancements in understanding the genetic mutations that affect cellular growth and invasion.
Latest Patents
Parsons holds a patent for his research titled "P13K pathway mutations in cancer." This patent highlights the critical role of protein kinases in pathways that influence cellular behavior. In his study, he analyzed 340 serine/threonine kinases for genetic mutations in colorectal cancers. His findings revealed mutations in eight genes, including three members of the phosphatidylinositol-3-kinase (PI3K) pathway. Notably, these mutations occurred in different tumors and did not overlap with mutations in PIK3CA or other non-serine-threonine kinase members of the PI3K pathway. This suggests that mutations in these genes have equivalent tumorigenic effects. His research underscores the PI3K pathway as a major target for mutational activation in colorectal cancers, opening new avenues for therapeutic intervention.
Career Highlights
Parsons is affiliated with The Johns Hopkins University, where he continues to contribute to groundbreaking research in cancer biology. His work has not only advanced scientific understanding but also provided potential pathways for developing new cancer therapies.
Collaborations
Parsons has collaborated with esteemed colleagues such as Tian-li Wang and Yardena Samuels. These partnerships have enriched his research and expanded the impact of his findings in the scientific community.
Conclusion
Donald William Parsons exemplifies the innovative spirit in cancer research through his patent and collaborative efforts. His work on the PI3K pathway mutations has significant implications for understanding and treating colorectal cancers.