Sierre, Switzerland

Dominique Roberge

USPTO Granted Patents = 14 

 

 

Average Co-Inventor Count = 4.3

ph-index = 3

Forward Citations = 31(Granted Patents)


Location History:

  • Sirre, CH (2012)
  • Sierre, CH (2007 - 2020)

Company Filing History:


Years Active: 2007-2020

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14 patents (USPTO):Explore Patents

Title: Dominique Roberge: Innovator in Morphinan Alkaloid Reactions

Introduction

Dominique Roberge, a notable inventor located in Sierre, Switzerland, holds an impressive portfolio of 14 patents. His innovations primarily focus on the field of continuous flow chemistry, particularly in the N-demethylation of morphinan alkaloids. Through his contributions, he has significantly advanced methodologies in this sector, showcasing his expertise and creativity as an inventor.

Latest Patents

One of Dominique's latest patents involves the N-demethylation of morphinan alkaloids. This patent discloses a continuous flow system for the N-demethylation of compounds containing tertiary N-methylamines, such as morphinan alkaloids. Specifically, it details the process of N-demethylation of oxymorphone-3,14-diacetate or 14-hydroxymorphinone-3,14-diacetate using highly active catalytic palladium (0) under elevated temperature and pressure conditions. This innovative approach paves the way for synthesizing noroxymorphone via aerobic palladium-catalyzed continuous flow N-demethylation.

Another significant patent by Roberge outlines a method for preventing the plugging of a continuous-reaction channel system. This occurs due to by-products generated during continuous reactions. The invention entails the generation of ultrasonic waves traveling through the channel system and coupling these waves into the process fluids, effectively mitigating potential issues that arise during continuous flow processes.

Career Highlights

Throughout his career, Dominique Roberge has been associated with prominent companies such as Lonza AG and Lonza Inc. His roles in these companies have allowed him to refine his skills and work on high-impact projects within the field of chemistry and pharmacology.

Collaborations

Dominique has collaborated with esteemed colleagues like Nikolaus H. Bieler and Bertin Zimmermann. These collaborations have further amplified the innovative output of his work, driving progress in his specialized field.

Conclusion

Dominique Roberge's contributions to the field of continuous flow chemistry, particularly in the N-demethylation processes, highlight his status as a pioneering inventor. With a total of 14 patents to his name and a career that includes valuable collaborations and roles in leading companies, Roberge continues to impact the landscape of innovation in the chemical industry.

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