Company Filing History:

10 out of 1,829

Sanofi-a Ventis Deutschland Gmbh

patents

2 out of 330

Aventis Pharma Deutschland, Gmbh

where one patent can have more than one assignee

Years Active: 2006-2011

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12 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 8076324 - Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them (2011-12-13),

2. 8048901 - 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups, processes for their preparation and their use as pharmaceuticals (2011-11-01),

3. 7968550 - Substituted N-aryl heterocycles, process for their preparation and their use as medicaments (2011-06-28),

4. 7872034 - Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals (2011-01-18),

5. 7365084 - Cycloalkyl-substituted amino acid derivatives, processes for their preparation and their use as pharmaceuticals (2008-04-29),

6. 7335671 - Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals (2008-02-26),

7. 7259177 - Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals (2007-08-21),

8. 7223788 - Substituted N-aryl heterocycles, process for their preparation and their use as medicaments (2007-05-29),

9. 7220876 - Arylcycloalkyl derivatives having branched side chains, processes for their preparation and their use as pharmaceuticals (2007-05-22),

10. 7173151 - Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals (2007-02-06),

11. 7160911 - Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals (2007-01-09),

12. 7148246 - Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals (2006-12-12),

Title: Dirk Gretzke: Innovating Cardiovascular Pharmaceuticals in Frankfurt

Introduction

Dirk Gretzke, an accomplished inventor based in Frankfurt-am-Main, Germany, has made significant contributions to the field of pharmaceuticals, particularly in the area of cardiovascular treatments. With a remarkable portfolio of 12 patents, his work focuses on innovative compounds that provide new solutions for serious heart conditions.

Latest Patents

Among his recent innovations are several noteworthy patents. One of them is centered on di(hetero)arylcyclohexane derivatives. This invention involves valuable pharmaceutical active compounds designed to inhibit ATP-sensitive potassium channels in the heart muscle. These compounds are particularly suitable for treating cardiovascular disorders such as arrhythmias and cardiac insufficiency. Furthermore, they play a crucial role in preventing sudden cardiac death.

Another significant patent by Gretzke details 1,3-substituted cycloalkyl derivatives that contain acidic, mainly heterocyclic groups. This invention includes processes for the preparation of these compounds, which are targeted towards treating metabolic disorders involving fatty acid metabolism and glucose utilization, particularly in conditions associated with insulin resistance.

Career Highlights

Dirk Gretzke has been associated with prominent pharmaceutical companies such as Sanofi-Aventis Deutschland GmbH and Aventis Pharma Deutschland GmbH. His professional journey reflects a deep commitment to advancing medical science through innovative pharmaceutical solutions.

Collaborations

Throughout his career, Gretzke has collaborated with notable colleagues, including Heiner Glombik and Eugen Falk. These partnerships have further enhanced his research initiatives and the development of his groundbreaking inventions.

Conclusion

With a solid foundation in pharmaceutical innovations, Dirk Gretzke continues to contribute to the medical community with his patented inventions, aiming to improve the treatment of serious cardiovascular conditions. His work exemplifies the vital role of inventors in shaping the future of healthcare through innovation.

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