Waltham, MA, United States of America

Dingyi Wen

USPTO Granted Patents = 10 


 

Average Co-Inventor Count = 6.2

ph-index = 5

Forward Citations = 56(Granted Patents)


Company Filing History:


Years Active: 2002-2019

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10 patents (USPTO):Explore Patents

Title: The Innovative Mind of Dingyi Wen

Introduction

Dingyi Wen, an accomplished inventor based in Waltham, Massachusetts, has made significant contributions to the field of biotechnology. With a remarkable portfolio of 10 patents, Wen's work focuses on innovative approaches to protein modification and neurite outgrowth enhancement.

Latest Patents

Among Wen's notable patents are methods of preventing and removing trisulfide bonds in proteins. This invention presents a novel approach for converting trisulfide bonds in proteins, such as antibodies, into disulfide bonds during chromatographic purification procedures. Additionally, Wen's methods inhibit the formation of trisulfide bonds during the cell culture production of these proteins, ultimately facilitating the production of monoclonal antibodies. Another significant patent involves Nogo receptor antagonists and methods for increasing neurite outgrowth. This invention encompasses immunogenic Nogo receptor-1 polypeptides, antibodies, soluble receptors, and fusion proteins, along with nucleic acids encoding these elements. The innovative methodologies and compositions developed by Wen offer exciting potential for therapeutic applications in neurobiology.

Career Highlights

Dingyi Wen has garnered experience at prestigious companies such as Biogen Idec and Curis, Inc. During his tenure, he has collaborated on various projects that have pushed the boundaries of existing knowledge and technology in the biotech sector. His commitment to research and development has positioned him as a thought leader in the imperative intersection of science and technology.

Collaborations

Wen has worked alongside distinguished colleagues, including R. Blake Pepinsky and Ellen A. Garber. These collaborations have fostered an environment of innovation, allowing for the successful exchange of ideas and expertise in their respective fields.

Conclusion

With a solid base of patents and significant industry experience, Dingyi Wen continues to push the frontiers of biotechnology. His work is instrumental in advancing techniques that have the potential to revolutionize therapeutic strategies, particularly in the realm of protein engineering and neurobiology. As he furthers his innovative endeavors, the impact of his contributions will undoubtedly resonate across the scientific community.

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