This inventor holds 1 USPTO granted patent. Top assignee: Schering Corporation. Active years: 2008.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2008
Title: The Innovations of Dingjiang Liu
Introduction
Dingjiang Liu is a notable inventor based in Edison, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the study of the Hepatitis C virus. His work has implications for drug discovery and structural biology.
Latest Patents
Dingjiang Liu holds a patent for the invention titled "Hepatitis C virus NS3 helicase subdomain I." This invention provides fragments of HCV NS3 helicase, and crystalline compositions thereof, based on subdomains of the HCV helicase protein. The protein fragments are stable, soluble, and structurally sound. They can be expressed at high levels in conventional expression systems, allowing for efficient, large-scale production for NMR-based screening applications and the production of [H,C,N]- and [C,N]-labeled polypeptides for structural NMR studies. Helicase fragments of the present invention are useful in advanced NMR techniques, such as NMR-based drug discovery techniques like SAR-by-NMR, in biological assays to discover inhibitors of HCV NS3 helicase, and to evaluate the mechanism of action and substrates for HCV NS3 helicase. Crystals of the present invention are useful for structure-based drug design studies using x-ray crystallographic techniques.
Career Highlights
Dingjiang Liu is associated with Schering Corporation, where he has contributed to various research initiatives. His work has been instrumental in advancing the understanding of the Hepatitis C virus and developing potential therapeutic strategies.
Collaborations
Some of his notable coworkers include Patricia C Weber and Paul Reichert. Their collaborative efforts have further enhanced the research output and innovation in their field.
Conclusion
Dingjiang Liu's contributions to biotechnology, particularly in the context of Hepatitis C research, highlight the importance of innovation in addressing global health challenges. His patent and collaborative work continue to pave the way for advancements in drug discovery and structural biology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile