Company Filing History:
1 out of 79 
1 out of 5 Years Active: 2013
Title: Diego Luis Viale: Innovator in Genetic Engineering
Introduction
Diego Luis Viale is a prominent inventor based in Buenos Aires, Argentina. He has made significant contributions to the field of genetic engineering, particularly in the area of tumor treatment. His innovative work has led to the development of a unique patent that holds promise for advancing cancer therapies.
Latest Patents
Diego Luis Viale holds a patent for an isolated DNA fragment of the SPARC human promoter and its use for driving the expression of a heterologous gene in tumor cells. This invention involves an isolated DNA sequence corresponding to a region of the SPARC gene human promoter from base pair -513 to base pair +35. This sequence is capable of driving the expression of a heterologous gene of interest, which can be associated with various promoter sequences, such as radiation-responsive, hypoxia-responsive, and free-radical-responsive sequences. The invention also encompasses constructs and DNA recombinant expression viral vectors that include the isolated sequence of the SPARC gene human promoter and at least one heterologous gene operably linked to it. The promoter sequence effectively drives the expression of the heterologous gene in tumor cells. Additionally, the patent provides pharmaceutical compositions and methods for treating tumors.
Career Highlights
Diego Luis Viale has worked with esteemed organizations such as the National Scientific and Technical Research Council (CONICET) and the Leloir Institute Foundation. His research and innovations have been instrumental in advancing the understanding of genetic mechanisms in cancer.
Collaborations
Diego has collaborated with notable colleagues, including Osvaldo Podhajcer and Eduardo Gustavo Alfredo Cafferata. These partnerships have further enriched his research and contributed to the success of his inventions.
Conclusion
Diego Luis Viale is a distinguished inventor whose work in genetic engineering has the potential to revolutionize cancer treatment. His patent on the SPARC human promoter showcases his innovative approach to addressing complex medical challenges.