Company Filing History:
Years Active: 2011
Title: Spotlight on Inventor Diane Maguire: Innovations in HDM2-Inhibitor Complexes
Introduction: Diane Maguire, an accomplished inventor from Downington, PA, is making significant strides in the field of biochemistry with her innovative research and development of HDM2-inhibitor complexes. With one patent to her name, she has laid the groundwork for potential advancements in cancer treatment through her groundbreaking work.
Latest Patents: Diane's notable patent, titled "HDM2-inhibitor complexes and uses thereof," includes crystallized HDM2 peptides. This invention details the X-ray diffraction patterns of the crystals, which are crucial for determining the three-dimensional structure of HDM2 at atomic resolution. By identifying ligand binding sites and modeling interactions between ligands and HDM2 amino acid residues, this patent opens the door to developing ligands that can serve as active agents, particularly inhibitors of MDM2 and HDM2 oncoproteins.
Career Highlights: Diane is currently associated with Ortho-McNeil Pharmaceutical Corporation, where she applies her expertise in drug development and biochemistry. Her commitment to research and innovation has positioned her as a key figure in her field, contributing valuable insights into the molecular dynamics of protein interactions.
Collaborations: Collaboration is crucial in the realm of scientific advancement, and Diane has worked alongside esteemed colleagues, such as Carsten Schubert and Bruce L Grasberger. Together, they have engaged in pivotal research initiatives that underscore the importance of teamwork in achieving significant breakthroughs.
Conclusion: Diane Maguire exemplifies innovation in the pharmaceutical industry with her patent on HDM2-inhibitor complexes. Her research not only contributes to the scientific community but also holds the potential for meaningful applications in cancer therapeutics. As Diane continues to explore the intricacies of biochemistry, she is sure to be a prominent figure in the realm of medical innovations.