Devora Cohen-Karni

Title: Devora Cohen-Karni: Innovator in Nucleotide Detection

Introduction

Devora Cohen-Karni is a notable inventor based in Cambridge, MA (US). She has made significant contributions to the field of molecular biology, particularly in the detection and quantification of hydroxymethylated nucleotides.

Latest Patents

Cohen-Karni holds a patent for her work titled "Detection and quantification of hydroxymethylated nucleotides in a polynucleotide preparation." This patent describes methods and compositions for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation. The goal is to map the location of hmNs in a genome, quantify their occurrence at selected loci, and correlate this occurrence with gene expression and phenotypic traits. The embodiments of her invention include the use of modifying enzymes alongside site-specific endonucleases to detect hmNs.

Career Highlights

Devora Cohen-Karni is associated with New England Biolabs, Inc., where she continues to advance her research and innovations. Her work has garnered attention for its potential applications in genetic research and biotechnology.

Collaborations

Cohen-Karni has collaborated with notable colleagues, including Jurate Bitinaite and Romualdas Vaisvila, contributing to a dynamic research environment.

Conclusion

Devora Cohen-Karni's innovative work in nucleotide detection exemplifies the intersection of science and technology, paving the way for advancements in genetic research. Her contributions are vital to understanding the complexities of gene expression and its implications.