Desmond Allen Kaplan

Title: Desmond Allen Kaplan: Innovator in Mass Spectrometry

Introduction

Desmond Allen Kaplan is a prominent inventor based in Billerica, MA (US). He has made significant contributions to the field of mass spectrometry, holding a total of 11 patents. His work focuses on enhancing the capabilities of mass spectrometry through innovative techniques and devices.

Latest Patents

Kaplan's latest patents include groundbreaking inventions such as "Triple quadrupole mass spectrometry coupled to trapped ion mobility separation." This invention provides a method for acquiring fragment ion spectra of substances in complex mixtures. It utilizes a trapped ion mobility spectrometer (TIMS) as the ion mobility separation device, coupled to a triple quadrupole mass filter assembly. The fragment ion spectra generated can be used for the identification of numerous proteins in complex mixtures or for the safe quantification of certain substances by their fragment ion mass spectra in a mass spectrometer with an upstream substance separator. The TIMS, particularly equipped with parallel accumulation, allows for prolonged ion accumulation duration, enhancing the detection of ion species without compromising the measurement capacity for fragment ion mass spectra.

Another notable patent is the "Contamination-proof ion guide for mass spectrometry." This invention relates to a radio frequency ion guide construction that minimizes contamination. It allows ions rejected by the RF confinement field to fly through and away from the ion guide electrodes, preventing them from hitting the sensitive electric potential defining surfaces of the ion guide electrodes. The design features forked or recessed electrode ends that may incorporate conductive mesh to cover gaps, further enhancing the performance of the ion guide.

Career Highlights

Throughout his career, Kaplan has worked with esteemed companies such as Bruker Daltonik GmbH and Bruker Daltonics, Inc. His experience in these organizations has contributed to his expertise in mass spectrometry and related technologies.

Collaborations

Kaplan has collaborated with notable colleagues, including Melvin Andrew Park and Mark Ridgeway. These partnerships have fostered innovation and advancement in their shared field of expertise.

Conclusion

Desmond Allen Kaplan's contributions to mass spectrometry through his patents and collaborations highlight his role as a leading inventor in the field. His innovative approaches continue to influence the development of advanced analytical techniques.