Company Filing History:
1 out of 2,405 
1 out of 1 Years Active: 2019-2022
Title: The Innovations of Deqian Bian
Introduction
Deqian Bian is a notable inventor based in Beijing, China. He has made significant contributions to the field of pharmaceuticals, particularly in the development of methods for resolving chiral compounds and inhibitors for various diseases. With a total of two patents to his name, Bian's work showcases his expertise and innovative approach to solving complex scientific challenges.
Latest Patents
Bian's latest patents include a resolution method for axial chiral enantiomers of lesinurad. This method utilizes inexpensive and readily available quinoline natural products and their derivatives as resolving agents. The process involves reacting these agents with lesinurad racemate in an organic solvent to form a salt, which is then dissociated by acidification to yield optically pure enantiomers. The method achieves a chiral purity of up to 100% for the (R)-configuration and 99.9% for the (S)-configuration, with total yields exceeding 90% and 80%, respectively. Another significant patent involves purine inhibitors of human phosphatidylinositol 3-kinase delta, which are useful for treating diseases such as inflammation, asthma, COPD, and cancer.
Career Highlights
Throughout his career, Deqian Bian has worked with prominent companies in the pharmaceutical industry, including Merck Sharp & Dohme Corporation and China Resources Saike Pharmaceutical Co., Ltd. His experience in these organizations has contributed to his development as an inventor and researcher.
Collaborations
Bian has collaborated with notable colleagues, including Meredeth Ann McGowan and Hua Zhou. These partnerships have likely enhanced his research and innovation efforts in the pharmaceutical field.
Conclusion
Deqian Bian's contributions to the field of pharmaceuticals through his innovative patents demonstrate his commitment to advancing medical science. His work in resolving chiral compounds and developing inhibitors for critical diseases highlights the importance of innovation in improving healthcare outcomes.
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