logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10221178 B1

PDFFull Text
Date of Patent:
Mar. 05, 2019

Filed:

Jun. 24, 2016

Purine inhibitors of human phosphatidylinositol 3-kinase delta

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Meredeth Ann McGowan, Boston, MA (US);

Hua Zhou, Acton, MA (US);

Jason D. Katz, Newton Highlands, MA (US);

Lihu Yang, Edison, NJ (US);

Joey L. Methot, Westwood, MA (US);

Kathryn Ann Lipford, Boston, MA (US);

Shimin Xu, Beijing, CN;

Ning Fu, Beijing, CN;

Guoquan Xu, Beijing, CN;

Deqian Bian, Beijing, CN;

Jianmin Fu, Beijing, CN;

Yabin Li, Beijing, CN;

Kin Chiu Fong, Shanghai, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

Patricia A. Shatynski

John C. Todaro

Primary Examiner:

Erich A Leeser

Int. Cl.
CPC ...
C07D 473/30 (2006.01); C07D 473/34 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); A61K 45/06 (2006.01); A61P 37/00 (2006.01); A61P 17/06 (2006.01); A61P 11/06 (2006.01); A61P 11/08 (2006.01); A61P 11/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 473/30 (2013.01); A61K 45/06 (2013.01); A61P 11/06 (2018.01); A61P 11/08 (2018.01); A61P 17/06 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 471/04 (2013.01); C07D 473/34 (2013.01); C07D 519/00 (2013.01);
Abstract

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.

Find Patent Forward Citations

Quick Actions:

McGowan, Meredeth. (2019). Purine inhibitors of human phosphatidylinositol 3-kinase delta (U.S. Patent No. 10221178). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10221178

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…