Dennis R Feller

Title: The Innovative Contributions of Dennis R. Feller

Introduction

Dennis R. Feller is a notable inventor based in Oxford, MS, who has made significant contributions to the field of pharmacology and biochemistry. With a total of seven patents to his name, Feller's work primarily focuses on the activation of peroxisome proliferator-activated receptors, which play a crucial role in lipid metabolism.

Latest Patents

One of Feller's latest patents is titled "Pterostilbene as an agonist for the peroxisome proliferator-activated receptor alpha isoform." This research investigates the hypolipidemic properties of resveratrol and its analogs, including pterostilbene, piceatannol, and resveratrol trimethyl ether. The study reveals that pterostilbene demonstrates the highest induction of PPARα, showing increases of 7- to 14-fold relative to control. The findings suggest that pterostilbene acts as a more effective hypolipidemic agent than resveratrol, similar to the effects of the hypolipidemic drug ciprofibrate.

Career Highlights

Throughout his career, Dennis R. Feller has worked with various organizations, including Molecular Design International, Inc. and the University of Mississippi. His research has contributed to advancements in understanding lipid-lowering drugs and their mechanisms of action.

Collaborations

Feller has collaborated with notable colleagues such as Duane Douglas Miller and Agnes M. Rimando, further enhancing the impact of his research in the scientific community.

Conclusion

Dennis R. Feller's innovative work in pharmacology and biochemistry has led to significant advancements in the understanding of lipid metabolism and the development of effective hypolipidemic agents. His contributions continue to influence the field and inspire future research.