Denise Bonen

Title: Denise Bonen: Research on Nod2 and Crohn’s Disease

Introduction

Denise Bonen is an inventor associated with Chicago, Illinois. Her patent work concerns Nod2, an intracellular signaling protein, and its potential relevance to Crohn’s disease.

Latest Patents

The available information lists one patent for Bonen: “Nod2 Nucleic Acids and Proteins.” The invention describes isolated nucleotide sequences encoding Nod2, Nod2 peptides, and antibodies that specifically bind to the protein. It also covers methods for detecting Nod2, screening compounds that may alter Nod2-associated signal transduction, and identifying Nod2 variant alleles. The patent further describes methods for identifying individuals who may have an increased risk of developing Crohn’s disease. Bonen is credited with 1 patent in the information provided.

Career Highlights

Bonen’s listed institutional affiliations include the University of Michigan and the University of Chicago. The available details do not specify her roles or dates of work at either institution.

Collaborations

Gabriel Nunez and Naohiro Inohara are identified as Bonen’s coworkers in connection with the research. Their work on Nod2 provides context for the collaborative research surrounding the protein and its possible relationship to Crohn’s disease.

Conclusion

Denise Bonen’s listed patent focuses on Nod2-related molecules, detection and screening methods, and approaches to assessing Crohn’s disease risk. The invention reflects the potential of molecular research to support understanding of disease-associated signaling.