Denis Deblois

Title: Innovator in Biosensor Technology - Denis Deblois

Introduction

Denis Deblois, a prominent inventor based in Montréal, Canada, has made significant contributions to the field of biosensor technology. His work primarily focuses on the development of innovative methods for monitoring biomolecule localization and trafficking within cells. With a unique perspective on cellular processes, his inventions aim to enhance our understanding of various biological mechanisms.

Latest Patents

Denis Deblois holds a patent for a groundbreaking invention titled "Renilla based biosensors for monitoring biomolecule localization and trafficking in cells." This invention describes Bioluminescence resonance energy transfer (BRET) biosensors designed to assess the intracellular localization, internalization, and trafficking of proteins, such as receptors, alongside other biomolecules, including second messengers. The biosensors operate based on the concentration and density of BRET donor and acceptor molecules within cellular compartments, rather than specific protein-protein interactions. Utilizing a GFP/Luc BRET pair, these tools offer robust and reproducible monitoring capabilities for protein trafficking and localization. Moreover, they possess the sensitivity required for high-throughput screening (HTS). The application of these biosensors spans various processes including protein endocytosis, recycling, receptor maturation, and biomolecule concentration assessment in diverse cellular compartments.

Career Highlights

Denis Deblois has had an impactful career, contributing his expertise to notable institutions such as McGill University and Université de Montréal. His work at these prestigious organizations has positioned him as a leader in developing biosensor technology, bridging advancements in research and practical applications in cellular biology.

Collaborations

Throughout his career, Denis has collaborated with esteemed colleagues, including Stéphane Alain Laporte and Yoon Namkung. These partnerships demonstrate his commitment to collaborative research, fostering innovation through teamwork and shared expertise in his field.

Conclusion

Denis Deblois stands out as a remarkable inventor whose work in biosensor technology has the potential to transform our approach to studying cellular dynamics. His patented innovations provide valuable tools for researchers, paving the way for future discoveries in molecular biology and biomedical applications. With a dedication to advancing science, Denis's contributions will undoubtedly continue to inspire and facilitate progress in the field.