Company Filing History:
2 out of 75 
1 out of 3,381 
Years Active: 1997-2010
Title: Dell Paielli: Innovator in Cancer Therapy and Thrombolysis
Introduction
Dell Paielli is a notable inventor based in Wyandotte, MI (US). He has made significant contributions to the fields of cancer therapy and thrombolysis through his innovative inventions. With a total of 2 patents, his work focuses on developing novel methods and compositions that have the potential to improve patient outcomes.
Latest Patents
One of Dell Paielli's latest patents is titled "Methods and compositions for cancer therapy using a novel adenovirus." This invention comprises a novel virus that can efficiently kill mammalian cancer cells. The virus produces a unique protein that converts two non-toxic prodrugs into potent chemotherapeutic agents. These agents are produced locally, aiding the virus in killing cancer cells and sensitizing them to radiation. In preclinical studies, the virus has demonstrated effectiveness in killing various mammalian cancer cells, either alone or in combination with prodrug therapy and/or radiation therapy. This invention may provide a safe and effective treatment for human cancer.
Another significant patent is "Peptide mediated enhancement of thrombolysis methods and compositions." This invention relates to peptides that decrease the half-life of active plasminogen activator inhibitor-1. It further includes methods and compositions for utilizing these peptides to enhance clot lysis. The implications of this work could lead to advancements in thrombolytic therapies.
Career Highlights
Dell Paielli has worked with esteemed organizations such as Henry Ford Health System and the University of Michigan. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of his notable coworkers include Daniel Lawrence and David Ginsburg. Their collaborative efforts have likely played a role in the development of his innovative patents.
Conclusion
Dell Paielli's contributions to cancer therapy and thrombolysis highlight his role as a significant inventor in the medical field. His innovative patents have the potential to transform treatment options for patients, showcasing the importance of research and development in healthcare.