The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Jan. 30, 2006
Svend O. Freytag, West Bloomfield, MI (US);
Jae Ho Kim, West Bloomfield, MI (US);
Ken Barton, Sterling Heights, MI (US);
Dell Paielli, Wyandotte, MI (US);
Svend O. Freytag, West Bloomfield, MI (US);
Jae Ho Kim, West Bloomfield, MI (US);
Ken Barton, Sterling Heights, MI (US);
Dell Paielli, Wyandotte, MI (US);
Henry Ford Health System, Detroit, MI (US);
Abstract
The invention comprises a novel virus that can kill mammalian cancer cells efficiently. The virus produces a novel protein that converts two non-toxic prodrugs into potent chemotherapeutic agents. These chemotherapeutic agents are produced locally and help the virus kill the cancer cells as well as sensitize them to radiation. In preclinical studies, the virus has proven effective at killing a variety of mammalian cancer cells either alone or when combined with prodrug therapy and/or radiation therapy. The invention may provide a safe and effective treatment for human cancer.