Company Filing History:
Years Active: 2018
Title: Deepti Singh - Innovator in Oligosaccharide-Protein Conjugation
Introduction
Deepti Singh is a prominent inventor based in New Delhi, India. She has made significant contributions to the field of biotechnology, particularly in the development of synthetic oligosaccharide-protein conjugates. Her innovative work has the potential to enhance vaccine development and diagnostic tools.
Latest Patents
Deepti Singh holds a patent for a process of conjugation and novel synthetic oligosaccharide-protein conjugates obtained thereof. The invention relates to an improved process of conjugation that yields synthetic oligosaccharide-protein (OS-PR) conjugates. This rapid process provides oligosaccharide-protein conjugates that are highly immunogenic and elicit specific and homogenous immune responses. The synthetic oligosaccharide consists of four to eight repeating units of respective monomers and includes at least one in-built terminal amino linker. This synthetic polysaccharide mimics natural polysaccharides obtained from gram-negative bacteria, such as serogroups A, C, Y, W, and X. The carrier protein is derived from gram-positive bacteria, such as tetanus toxoid or CRM197, or their recombinant versions. The conjugation chemistry involves thio-ether linkage, and the complete process time ranges from 14 to 22 hours. These oligosaccharide-protein conjugates are useful in the production of monovalent or multivalent combination vaccines and as diagnostic tools.
Career Highlights
Deepti Singh is currently employed at MSD Wellcome Trust Hilleman Laboratories Pvt. Ltd. Her work at this esteemed organization has allowed her to focus on innovative solutions in the field of vaccine development.
Collaborations
Deepti has collaborated with notable colleagues, including Davinder Gill and Manoj Kumar Chhikara, to advance her research and development efforts.
Conclusion
Deepti Singh's contributions to the field of biotechnology, particularly through her patented process of conjugation, highlight her role as an innovator. Her work has the potential to significantly impact vaccine development and diagnostic methodologies.