Deena J Small

Title: **Deena J Small: Innovator in Jagged/Notch Protein Research**

Introduction

Deena J Small, based in Scarborough, Maine, is a distinguished inventor recognized for her contributions to the field of therapeutic and diagnostic methods involving Jagged/Notch proteins and nucleic acids. With a total of two patents to her name, her innovative work has the potential to significantly impact medical science and treatment methodologies.

Latest Patents

Deena's most recent patent revolves around therapeutic and diagnostic methods and compositions that utilize Jagged/Notch proteins and nucleic acids. This notable invention explores the critical roles these elements play in the signaling pathway related to endothelial cell migration and differentiation. It encompasses the development of substantially purified Jagged proteins as well as nucleic acids encoding these proteins. This innovation also extends to soluble Jagged proteins, which offer therapeutic and diagnostic avenues for diseases linked with the Jagged/Notch signaling pathway, including angiogenesis, differentiation, and gene expression regulation.

Career Highlights

Deena J Small is associated with the Maine Medical Center Research Institute, where her research and innovations continue to advance medical knowledge and therapeutic approaches in her field. Her work contributes significantly to the understanding of crucial biological processes and offers potential avenues for treating various conditions and disorders.

Collaborations

Throughout her career, Deena has collaborated with esteemed colleagues such as Thomas Maciag and Ann B Zimrin. These collaborations foster a rich exchange of ideas and enhance the innovative efforts within her research environment, promoting advancements in the understanding of Jagged/Notch signaling.

Conclusion

Deena J Small stands out as a prominent inventor whose research on Jagged/Notch proteins is paving the way for significant breakthroughs in therapeutic and diagnostic methodologies. Her ongoing contributions at the Maine Medical Center Research Institute, along with her collaborations, ensure that her impact on science and medicine will be felt for years to come.