Houston, TX, United States of America

Deborah R Wilson


 

Average Co-Inventor Count = 4.7

ph-index = 4

Forward Citations = 164(Granted Patents)


Company Filing History:


Years Active: 1996-2019

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7 patents (USPTO):Explore Patents

Title: Innovations in Gene Therapy: The Work of Deborah R. Wilson

Introduction

Deborah R. Wilson, an accomplished inventor based in Houston, TX, has made significant contributions to the field of gene therapy, with a total of seven patents to her name. Her inventive work primarily focuses on non-viral gene therapy methods and compositions aimed at treating hyperproliferative diseases in humans.

Latest Patents

Among her latest patents, one highlights methods and compositions for non-viral gene therapy specifically designed for hyperproliferative diseases. This invention revolves around innovative lipid formulations that create stable liposome structures, facilitating efficient in vivo nucleic acid transfer. Furthermore, the methods aim for cell-specific targeting, ensuring precise treatment of affected cells.

Another noteworthy patent addresses the purification of adenoviral vectors, improving yields when grown in cell culture systems. Wilson's research has demonstrated that utilizing low-medium perfusion rates in an attached cell culture system significantly enhances adenoviral production. Moreover, her methods emphasize serum-free conditions and the use of detergent lysis for effective purification, enabling simplification of the purification process while maintaining high-quality virus preparations.

Career Highlights

Deborah's contributions to science and technology have been realized through her work with notable companies such as Introgen Therapeutics Inc. and Baylor College of Medicine. Her expertise has shaped advancements in the biopharmaceutical field, particularly in therapies that target serious diseases.

Collaborations

Throughout her career, Wilson has collaborated with esteemed colleagues, including Shuyuan Zhang and Capucine Thwin. These partnerships have further enriched her research endeavors and fostered innovative approaches to medical challenges.

Conclusion

Deborah R. Wilson stands out as a prominent inventor in the realm of gene therapy, with a focus on developing methods and compositions that significantly contribute to healthcare advancements. Her work not only showcases her ingenuity but also promises improvements in the treatment of hyperproliferative diseases, reflecting the vital role of innovation in medicine.

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