The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
May. 24, 2000
Rajagopal Ramesh, Houston, TX (US);
Jack A. Roth, Houston, TX (US);
Tomoyuki Saeki, Tokyo, JP;
Deborah R. Wilson, Houston, TX (US);
Rajagopal Ramesh, Houston, TX (US);
Jack A. Roth, Houston, TX (US);
Tomoyuki Saeki, Tokyo, JP;
Deborah R. Wilson, Houston, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Introgen Research Institute, Inc., Austin, TX (US);
Abstract
The present invention relates to non-viral gene therapy methods and compositions for treatment of hyperproliferative disease in humans. More specifically, the invention is directed, in one embodiment, to lipid formulations which form stable liposome structures, capable of efficient in vivo nucleic acid transfer. In other embodiments, methods and compositions are directed to liposome transfer of anti-proliferative nucleic acids, wherein the transfer of the nucleic acids is cell specific via cell specific targeting moieties. The present invention, thus provides non-viral, liposome compositions and methods of gene transfer particularly useful for targeting and treating hyperproliferative disease.