This inventor holds 3 USPTO granted patents and 4 published patent applications and 1 EPO patent. Top assignees: Irm LLC, Novartis Ag. Active years: 2007-2020.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2007-2020
Title: Innovations and Contributions of Deborah A Knee
Introduction
Deborah A Knee is a prominent inventor based in Del Mar, CA (US). She has made significant contributions to the field of immunology and cancer therapy, holding a total of 3 patents. Her work focuses on enhancing immune responses and developing novel therapeutic methods for cancer treatment.
Latest Patents
One of her latest patents is titled "Compositions and methods of use for augmented immune response and cancer therapy." This invention provides antibody compositions, including antibodies, engineered antibodies, and antibody fragments that bind to a tumor necrosis factor receptor superfamily member (i.e., 18). The provided compositions are useful in enhancing CD4+ and CD8+ T cell responses, as well as in the treatment, amelioration, and prevention of diseases that can be counteracted with an augmented immune response, such as cancers. Additionally, the invention includes polynucleotides and vectors that encode such molecules, along with host cells that harbor the polynucleotides or vectors, and pharmaceutical compositions that comprise these molecules and methods of use thereof. Another significant patent is "Methods and compositions for inducing apoptosis in cancer cells with an anti-DR5 antibody." This patent describes anti-DR5 antibody agonists, which, when combined with apoptosis-inducing agents, synergistically induce apoptosis in cancer cells.
Career Highlights
Throughout her career, Deborah has worked with notable companies such as Irm LLC and Novartis AG. Her innovative approaches and research have positioned her as a key figure in the development of cancer therapies.
Collaborations
Deborah has collaborated with esteemed colleagues, including Marc Nasoff and Quinn L Deveraux, contributing to the advancement of her research and inventions.
Conclusion
Deborah A Knee's work exemplifies the intersection of innovation and healthcare, particularly in the realm of cancer treatment and immune response enhancement. Her patents and collaborations reflect her commitment to advancing medical science and improving patient outcomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile