Company Filing History:
Years Active: 2011
Title: Davide Comoletti: Innovator in Autism Spectrum Disorder Treatment
Introduction
Davide Comoletti is a notable inventor based in San Diego, CA. He has made significant contributions to the field of neuroscience, particularly in the treatment of autism spectrum disorders. His innovative approach focuses on the delivery of antioxidant agents to enhance the expression of neuroligins, which are crucial proteins in the brain.
Latest Patents
Comoletti holds a patent for a method of promoting the delivery of an antioxidant agent to a cell expression neuroligin. This patent outlines methods and compositions for treating autism spectrum disorders by administering an antioxidant or agent that stabilizes or enhances the expression of altered neuroligins. A key aspect of this invention includes site-specific delivery of the antioxidant to the endoplasmic reticulum (ER) to reverse incorrect disulfide binding of the protein neuroligin. The patent also describes a method of targeting the antioxidant to neuroligin by utilizing the calcium binding or other recognition sites of neuroligin to bind the antioxidant. The antioxidant can be cysteamine linked to a molecule that binds to a specific binding site.
Career Highlights
Comoletti's career is marked by his dedication to advancing scientific understanding and treatment options for autism spectrum disorders. His work has the potential to significantly impact the lives of individuals affected by these conditions. He is affiliated with the University of California, where he continues to conduct research and develop innovative solutions.
Collaborations
Comoletti has collaborated with esteemed colleagues such as Palmer Taylor and Lori Jennings. These partnerships have fostered a collaborative environment that enhances the research and development of effective treatments.
Conclusion
Davide Comoletti is a pioneering inventor whose work in the field of autism spectrum disorder treatment showcases the importance of innovation in neuroscience. His patented methods for delivering antioxidant agents represent a significant advancement in therapeutic strategies.