The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2011
Filed:
May. 10, 2005
Palmer Taylor, Del Mar, CA (US);
Davide Comoletti, San Diego, CA (US);
Lori Jennings, San Diego, CA (US);
Robyn Flynn, Calgary, CA;
Palmer Taylor, Del Mar, CA (US);
Davide Comoletti, San Diego, CA (US);
Lori Jennings, San Diego, CA (US);
Robyn Flynn, Calgary, CA;
The Regents of the University of California, Oakland, CA (US);
Abstract
Provided are methods and compositions for treating autism spectrum disorders by administering an antioxidant or agent that stabilize or enhance expression of altered neuroligins. An aspect of the disclosure includes site-specific delivery of the antioxidant to the endoplasmic reticulum (ER) to reverse incorrect disulfide binding of the protein neuroligin. Also disclosed is a method of targeting the antioxidant to neuroligin by using the calcium binding or other recognition site of neuroligin to bind the antioxidant. The antioxidant can be cysteamine linked to a molecule which binds to a binding site.