David Younger

Title: David Younger: Innovator in Protein-Protein Interactions

Introduction

David Younger is a prominent inventor based in Seattle, WA, known for his significant contributions to the field of protein-protein interactions. With a total of eight patents to his name, he has made remarkable strides in understanding and manipulating biological systems for pharmaceutical applications.

Latest Patents

Younger’s latest patents include innovative methods for efficiently characterizing protein-protein interactions. This patent provides methods for improving libraries for screening protein-protein interactions by excluding amino acid substitutions that are predicted to have a redundant or minimal effect on binding between protein binding partners. Another notable patent focuses on high-throughput screening methods to identify small molecule targets. This patent outlines methods for identifying pairs of protein binding partners, mutations of which may inform the discovery of pharmaceutically useful small molecules. These methods may allow for the adaptation of the native protein degradation system to modulate specific disease targets at the protein level, particularly for targets that have long been considered undruggable.

Career Highlights

Throughout his career, David Younger has worked with notable organizations such as A-alpha Bio, Inc. and the University of Washington. His work has significantly impacted the field of biochemistry and drug discovery, showcasing his expertise and innovative thinking.

Collaborations

Younger has collaborated with esteemed colleagues, including Randolph Lopez and David Baker. These partnerships have further enhanced his research and development efforts in the realm of protein interactions.

Conclusion

David Younger stands out as a leading inventor in the field of protein-protein interactions, with a strong portfolio of patents that reflect his innovative contributions. His work continues to pave the way for advancements in pharmaceutical research and development.