Houston, TX, United States of America

David Y Graham


Average Co-Inventor Count = 3.0

ph-index = 3

Forward Citations = 63(Granted Patents)


Company Filing History:


Years Active: 1989-2000

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4 patents (USPTO):Explore Patents

Title: David Y Graham: Innovator in Viral Research

Introduction

David Y Graham is a prominent inventor based in Houston, Texas, known for his significant contributions to the field of viral research. He holds four patents that focus on innovative methods for detecting and diagnosing viral infections, particularly Norwalk virus and mycobacterial infections. His work has paved the way for advancements in diagnostic assays and vaccine development.

Latest Patents

Graham's latest patents include groundbreaking work on polyclonal and monoclonal antibodies to Norwalk virus. He developed methods for synthesizing double-stranded cDNA from nucleic acid extracted from Norwalk virus purified from stool specimens. One notable clone, pUCNV-953, was isolated from a cDNA library and demonstrated specificity through hybridization assays. This cDNA reacted with post-infection stool samples from Norwalk volunteers and with highly purified Norwalk virus, while showing no reaction with other common enteric viruses. His research also led to the detection of the Norwalk virus's single-stranded RNA genome, facilitating the rapid cloning of the entire genome and the establishment of sensitive diagnostic assays. Additionally, he has worked on a mycobacterial genus-specific DNA probe, providing a more sensitive test for mycobacterial infections.

Career Highlights

David Y Graham is affiliated with Baylor College of Medicine, where he continues to advance his research in viral diagnostics. His innovative approaches have significantly improved the sensitivity and specificity of tests for viral infections, contributing to better public health outcomes.

Collaborations

Graham has collaborated with notable researchers in his field, including Mary K Estes and Xi Jiang. Their combined expertise has further enhanced the impact of his research on viral diagnostics.

Conclusion

David Y Graham's contributions to viral research and diagnostics exemplify the importance of innovation in the medical field. His patents and ongoing work continue to influence the development of effective diagnostic tools and vaccines.

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