Location History:
- Sunol, CA (US) (1985 - 1990)
- San Francisco, CA (US) (2002)
Company Filing History:
3 out of 3 
1 out of 11 
1 out of 832,961 Years Active: 1985-2002
Title: Profile of Inventor David W Rasnick
Introduction
David W Rasnick is an innovative inventor based in Sunol, California. He holds five patents that contribute to advancements in the pharmaceutical and biochemical fields. His work focuses primarily on enhancing methods for synthesizing compounds and detecting proteases, which are crucial for understanding various disease states.
Latest Patents
Among his notable inventions, Rasnick has developed significant patents including:
1. **Peptidyl sulfonyl imidazolides as selective inhibitors of serine proteases** - This patent discloses novel alpha-amino and peptidyl sulfonyl imidazolides, along with methods for their synthesis. It details the use of these compounds in pharmaceutical compositions aimed at treating diseases characterized by the over-activity of serine proteases. Also, it introduces novel synthetic methods for synthesizing sulfonyl derivatives from thioic acid S-esters.
2. **Method of detecting cysteine proteases** - This invention involves peptide thioneamides as synthetic substrates for cysteine proteases. The patents describe peptides that include blocked or unblocked amino acids, with terminal thionated carboxy groups, forming a thioneamide linkage. This patent also encompasses methods and kits utilizing these peptide thioneamides for research and diagnostic purposes.
Career Highlights
David W Rasnick has made significant contributions during his tenure at various organizations, including Enzyme Systems Products. His work has helped bridge gaps in scientific knowledge and has propelled forward the application of protease inhibitors in medicine.
Collaborations
Throughout his career, Rasnick has collaborated with prominent individuals such as Kyujin Cho and Eugene R Bissell. These partnerships have fostered a rich environment for innovation and have led to the successful development of his patented technologies.
Conclusion
David W Rasnick stands out as a leading figure in the field of biochemical innovation. His patents and collaborative efforts continue to influence the industry, providing vital tools for the detection and treatment of diseases linked to protease activity.