David Uhen is an accomplished inventor based in Burlington, WI (US), known for his significant contributions to the field of biopharmaceutical monitoring. With a total of 13 patents to his name, Uhen has developed innovative solutions that enhance the efficiency and accuracy of monitoring biopharmaceutical solutions.

Latest Patents

One of Uhen's latest patents focuses on optical sensors for monitoring biopharmaceutical solutions in single-use containers. This invention provides disposable, pre-sterilized, and pre-calibrated sensor components that interact with a sensor system, which includes a disposable fluid conduit or bioreactor bag and a reusable sensor assembly. The design incorporates an optical bench or inset optical component that is integrated within the disposable fluid conduit or bioreactor bag, allowing for an optical light path through the conduit or bag. The sensor systems are equipped to store sensor-specific information, such as calibration and production details, in a non-volatile memory chip located on both the disposable fluid conduit or bag and the reusable sensor assembly. Additionally, methods for calibrating the sensor and determining a target property of an unknown fluid are disclosed, making the devices suitable for turbidity sensing.

Another notable patent involves single-use sensors in bioreactors, biotech purification, and bioprocessing. This invention features presterilized manifolds with disposable multifunctional sensors designed for sterile packaging and single-use applications. These manifolds, equipped with disposable tubing and flexible-wall containers, are adapted to interact with other equipment operated by a controller and a flow-imparting unit. This innovation ensures automated and accurate delivery or purification of biotechnology fluid. The disposable sensor monitors parameters such as pH, oxygen, and electrical conductivity, either individually or in combination, and can connect to a separate user interface.

Career Highlights

Throughout his career, David Uhen has worked with prominent companies, including Parker-Hannifin Corporation and Sencal, LLC. His experience in these organizations has contributed to his expertise in developing advanced sensor technologies for the biopharmaceutical industry.

Collaborations

Uhen has collaborated with notable professionals in his field, including Karl G. Schick and Kurt A. Reichold. These collaborations have further enriched his work and led to the development of innovative solutions in biopharmaceutical monitoring.

Conclusion

David Uhen's contributions to

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