David S Bredt

Title: David S Bredt: Innovator in Nitric Oxide Research

Introduction

David S Bredt is a prominent inventor based in Baltimore, MD (US). He has made significant contributions to the field of medical science, particularly in the area of treatments for male sexual dysfunction and nitric oxide synthase research. With a total of 3 patents, Bredt's work has had a lasting impact on both clinical practices and scientific understanding.

Latest Patents

Bredt's latest patents include innovative methods and devices for regulating penile erection and urethral function. These treatments utilize inhibitors of nitric oxide synthase and precursors of nitric oxide to relax or contract the muscles of the corpus cavernosum and the urethra. Another notable patent involves the purification and molecular cloning of nitric oxide synthase. This method provides a homogeneous preparation of the enzyme, which is essential for raising antibodies that serve as useful immunohistochemical reagents. These antibodies help localize calmodulin-dependent nitric oxide synthase to various anatomical sites, including the retina, intestine, adrenal gland, and vasculature.

Career Highlights

Throughout his career, Bredt has worked with esteemed institutions, including The Johns Hopkins University. His research has paved the way for advancements in understanding nitric oxide's role in various physiological processes. His innovative approaches have contributed to the development of new therapeutic strategies.

Collaborations

Bredt has collaborated with notable figures in the field, including Solomon H Snyder and Arthur L Burnett. These partnerships have further enriched his research and expanded the impact of his work.

Conclusion

David S Bredt's contributions to nitric oxide research and treatments for male sexual dysfunction highlight his role as a leading inventor in the medical field. His patents and collaborations continue to influence scientific research and clinical applications.