Location History:
- South San Francisco, CA (US) (2022)
- San Francisco, CA (US) (2011 - 2023)
- Oxford, GB (2020 - 2023)
Company Filing History:
13 out of 1,820 
9 out of 532 
2 out of 4 Years Active: 2011-2023
Title: **David Ruff: Innovator in Nucleic Acid Amplification**
Introduction
David Ruff, a prominent inventor based in San Francisco, CA, has made significant contributions to the field of molecular biology through his innovative work in nucleic acid amplification. With a remarkable portfolio of 25 patents, Ruff continues to push the boundaries of scientific discovery and innovation.
Latest Patents
Among his latest patents is a groundbreaking method for nucleic acid amplification, which offers various methodologies, compositions, kits, and systems. This invention allows for the partial denaturing of nucleic acids during amplification, enabling processes that do not require complete denaturation. Notably, the methods utilize an enzyme that facilitates homologous recombination alongside a polymerase, effectively simplifying the amplification process into a single reaction vessel and continuous liquid phase. Additionally, his patent on multiplex amplification of polynucleotides caters to analyzing samples with amplified assays performed in multiplex fashion, further enhancing the efficiency of gene expression analysis.
Career Highlights
David Ruff's career is marked by significant roles at leading biotechnology firms, specifically at Life Technologies Corporation and Applied Biosystems, LLC. His expertise in nucleic acid technology has contributed to advancements that are widely utilized in research and clinical applications, cementing his reputation as a key figure in biotechnology innovation.
Collaborations
Throughout his career, Ruff has collaborated with talented individuals in the field, including Shiaw-Min Chen and Chieh-Yuan Li. These partnerships have further enriched the scope of his work and fostered an environment of creativity and advancement in nucleic acid research.
Conclusion
David Ruff exemplifies the spirit of innovation in the biotechnology sector. His extensive patent portfolio and collaborative efforts reflect a commitment to advancing molecular techniques that have significant implications for research and healthcare. As he continues to develop new methodologies, his contributions are likely to influence the future of genetic analysis and diagnostics.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.