The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Dec. 20, 2018
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Shiaw-Min Chen, Fremont, CA (US);

David W. Ruff, San Francisco, CA (US);

Harrison Leong, San Francisco, CA (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6844 (2018.01); G16B 25/00 (2019.01); G16B 40/00 (2019.01); G16B 25/20 (2019.01); G16B 40/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6844 (2013.01); G16B 25/00 (2019.02); G16B 25/20 (2019.02); G16B 40/00 (2019.02); G16B 40/10 (2019.02);
Abstract

Various embodiments of methods for analyzing proximity binding assay (PBA) data are disclosed. Proximity binding assays as a class of analyses offer the advantages of the sensitivity and specificity of biorecognition binding, along with the exponential signal amplification offered by a variety of oligonucleotide amplification reactions, such as the polymerase chain reaction (PCR). However, as various proximity binding assays have reaction kinetics governed by an additional step of the binding of a biorecognition probe (BRP) with a target molecule, there is a need for methods for the analysis of PBA data that are particularly suited to the unique characteristics of such data.


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