King of Prussia, PA, United States of America

David Paolella


 

Average Co-Inventor Count = 8.0

ph-index = 1


Company Filing History:


Years Active: 2017-2018

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2 patents (USPTO):Explore Patents

Title: **David Paolella: Innovator in Affinity Chromatography and Therapeutic Development**

Introduction

David Paolella is an accomplished inventor based in King of Prussia, Pennsylvania. He holds two patents that showcase his significant contributions to the fields of affinity chromatography and therapeutic agent development. His work is instrumental in advancing purification techniques and enhancing the efficacy of therapeutic agents.

Latest Patents

Paolella's latest patents include groundbreaking compounds for affinity chromatography, primarily aimed at purifying serum albumin, particularly human serum albumin (HSA), along with fusion proteins. These inventions encompass methods for extending the half-life of therapeutic agents, especially therapeutic peptide agents and small molecules. His approach involves the conjugation of specific compounds to these therapeutic agents, which upon administration, binds to human serum albumin, resulting in a prolonged release of the therapeutic agent, thus improving treatment outcomes.

Career Highlights

David Paolella is currently affiliated with GlaxoSmithKline Intellectual Property Development Limited, where he plays a vital role in research and development. His expertise not only exemplifies innovation in drug formulation but also highlights the importance of intellectual property in the pharmaceutical industry.

Collaborations

During his career, Paolella has collaborated with notable colleagues such as Peter Kumpalume and Oliver Schon. Together, they have contributed significantly to advancing methodologies that support the pharmaceutical industry’s quest for more effective therapeutic solutions.

Conclusion

David Paolella's inventive spirit and dedication to improving therapeutic modalities through affinity chromatography and drug release mechanisms underscore his impact on the field. His patents are a testament to his innovative approach and commitment to advancing health care solutions, showcasing the vital role of inventors in scientific progress.

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