The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Oct. 01, 2014
Glaxosmithkline Intellectual Property Development Limited, Middlesex, GB;
Peter Kumpalume, Stevenage, GB;
Oliver Schon, Stevenage, GB;
Christine Patricia Donahue, Waltham, MA (US);
Ghotas Evindar, Waltham, MA (US);
David I. Israel, Waltham, MA (US);
David Paolella, King of Prussia, PA (US);
Letian Kuai, Waltham, MA (US);
Ninad V. Prabhu, Waltham, MA (US);
GlaxoSmithKline Intellectual Property Development Limited, Brentford, Middlesex, GB;
Abstract
Compounds useful for affinity chromatography as presented, more particularly for use in affinity chromatography to purify serum albumin, especially human serum albumin (HSA) and fusion proteins thereof. Methods for extending the half-life of therapeutic agents are also presented, particularly therapeutic peptide agents and small molecules, such as by conjugation of compounds described herein to the therapeutic peptide or small molecule, which upon administration, binds to HSA, thereby providing a prolonged release of the therapeutic agent.