David P Yee

Title: David P Yee: Innovator in Tumor Necrosis Factor Receptors and Protease-Activated Receptors

Introduction

David P Yee is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of polypeptides and polynucleotides related to tumor necrosis factor receptors and protease-activated receptors. With a total of 6 patents, his work has implications for drug development and cellular signaling.

Latest Patents

One of his latest patents is for the Soluble receptor BR43x2, which includes soluble, secreted tumor necrosis factor receptor polypeptides and the polynucleotides encoding them. This invention provides methods for detecting ligands, agonists, and antagonists, and may also be utilized in modulating B cell activation. Another significant patent is for the Protease-activated receptor PAR4 (ZCHEMR2). This invention relates to polynucleotide and polypeptide molecules that mediate biological responses in response to proteases. The PAR4 receptor serves as a target in drug screening, allowing for the identification of both proteinaceous and non-proteinaceous PAR4 agonists and antagonists.

Career Highlights

Throughout his career, David P Yee has worked with notable companies, including Zymogenetics, Inc. His innovative work has positioned him as a key figure in the biotechnology sector, contributing to advancements in therapeutic targets and drug discovery.

Collaborations

David has collaborated with esteemed colleagues such as Scott R Presnell and Donald C Foster. Their combined expertise has furthered research and development in their respective fields.

Conclusion

David P Yee's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the development of therapeutic strategies in medicine.