The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2010
Filed:
Jul. 20, 2006
Jane A. Gross, Seattle, WA (US);
Wenfeng Xu, Mukilteo, WA (US);
Karen L. Madden, Bellevue, WA (US);
David P. Yee, Cambridge, MA (US);
Jane A. Gross, Seattle, WA (US);
Wenfeng Xu, Mukilteo, WA (US);
Karen L. Madden, Bellevue, WA (US);
David P. Yee, Cambridge, MA (US);
Zymogenetics, Inc., Seattle, WA (US);
Abstract
Soluble, secreted tumor necrosis factor receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise one cysteine-rich repeat that is homologous to other tumor necrosis factor receptors, such as transmembrane activator and CAML-interactor (TACI). The polypeptides may be used for detecting ligands, agonists and antagonists. The polypeptides may also be used in methods that modulate B cell activation.