David M Ornitz

Title: The Innovations of David M Ornitz

Introduction

David M Ornitz is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of biomedical research, particularly in the area of growth factor receptors. With a total of 2 patents, his work has had a substantial impact on understanding cellular interactions and growth factor signaling.

Latest Patents

Ornitz's latest patents include a system for assaying binding to a heparin-binding growth factor receptor. This invention describes a homogeneous population of cells that possess a number of cell surface low-affinity heparin-binding growth factor (HBGF) sites per cell that is less than 20% of the number found on wild-type CHO-K1 cells. Additionally, these cells have at least three times the number of cell surface high-affinity HBGF receptors per cell compared to such CHO-K1 cells. The patent also details an assay system utilizing these specialized cells, which express a substantial number of surface high-affinity HBGF receptors.

Career Highlights

Throughout his career, David M Ornitz has worked with prestigious organizations, including Children's Medical Center Corporation and Harvard College. His research has contributed to advancements in the understanding of growth factors and their receptors, which are crucial for various biological processes.

Collaborations

Ornitz has collaborated with notable colleagues such as Avner Yayon and Michael Klagsbrun. These partnerships have further enriched his research and innovations in the field.

Conclusion

David M Ornitz's contributions to the field of biomedical research through his patents and collaborations highlight his role as a significant inventor. His work continues to influence the understanding of growth factor interactions and their implications in health and disease.