Location History:
- Knoxville, TN (US) (2001)
- Urbana, IL (US) (2011 - 2012)
- Boonville, IN (US) (2013 - 2017)
- Washington, DC (US) (2018 - 2019)
- Arlington, VA (US) (2021 - 2024)
Company Filing History:
12 out of 2,340 
1 out of 832,680 Years Active: 2001-2024
Title: David M Knapp: Innovator in Amphotericin B Derivatives
Introduction
David M Knapp, an accomplished inventor located in Boonville, Indiana, has made significant contributions to the field of pharmaceutical science. With a portfolio boasting 12 patents, he is recognized for his innovative work on amphotericin B derivatives, aiming to enhance therapeutic efficiency while minimizing toxicity.
Latest Patents
One of Knapp's latest patents focuses on amphotericin B derivatives characterized by their improved therapeutic index. These innovative derivatives are designed to exhibit reduced toxicity while retaining their anti-fungal activity. Among these advancements are C16 urea derivatives and various deoxy derivatives, including C3, C5, C8, C9, C11, C13, and C15 modifications of amphotericin B. Additionally, the invention incorporates C3′ or C4′ modifications of the mycosamine appendage of amphotericin B. The patent outlines methods for producing these derivatives, formulations that include them, and recommended applications in therapeutic contexts.
Career Highlights
Knapp is currently associated with the University of Illinois, where he continues to research and develop innovative pharmaceutical solutions. His work primarily involves exploring and enhancing the therapeutic properties of existing antifungals, making significant strides in improving patient safety and efficacy in treatment regimens.
Collaborations
Throughout his career, David has collaborated with notable scientific minds such as Martin D Burke and Eric P Gillis. These partnerships have undoubtedly fueled his inventive processes and expanded the scope of his research, leading to breakthroughs in pharmaceutical developments.
Conclusion
David M Knapp's work exemplifies the profound impact that innovative mindsets can have on healthcare solutions. His commitment to developing safer amphotericin B derivatives not only underscores his expertise but also promises to improve outcomes for patients affected by fungal infections. With numerous patents to his name, Knapp continues to inspire the next generation of inventors in the pharmaceutical field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.