David M Briscoe

Title: The Innovative Contributions of David M. Briscoe

Introduction: David M. Briscoe, based in Sharon, MA, is a notable inventor with significant contributions to the field of immunology. With two patents to his name, his work focuses on advancing methods to modulate the immune response, particularly in relation to organ transplants.

Latest Patents: Briscoe's recent patents reflect his expertise in immunomodulation. The first patent, titled "Methods and compositions for immunomodulation," explores the modulation of the immune system through the regulation of Sema3F levels and activity. It aims to suppress allograft rejection and inflammation, providing a possible therapeutic avenue by administering Sema3F agonists or inhibitors. His second patent, "Treatment of chronic allograft rejection with anti-angiogenic agents," outlines methods for inhibiting chronic rejection of organ transplants. This invention involves administering effective amounts of anti-angiogenic agents to mitigate allograft rejection, either alone or in conjunction with immunosuppressive agents.

Career Highlights: David M. Briscoe is associated with the Children's Medical Center Corporation, where his research contributes to improving patient outcomes in transplant medicine. His dedication to advancing medical science is evident in his focus on innovative treatments for complex immunological challenges.

Collaborations: Throughout his career, Briscoe has worked alongside esteemed colleagues, including Michael Klagsbrun and Sarah Bruneau. These collaborations highlight the importance of teamwork in the advancement of scientific research and innovation.

Conclusion: David M. Briscoe's contributions to immunology through his patents are paving the way for improved therapies in organ transplant rejection. His innovative approaches, in collaboration with other professionals, exemplify the vital role inventors play in the advancement of medical science.