The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Jun. 01, 2015
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventors:
David M. Briscoe, Sharon, MA (US);
Michael Klagsbrun, Newton, MA (US);
Sarah Bruneau, Boston, MA (US);
Nora Kochupurakkal, Boston, MA (US);
Hironao Nakayama, Boston, MA (US);
Assignee:
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/48 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/177 (2013.01); A61K 38/482 (2013.01); A61K 45/06 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); C12Y 304/21 (2013.01); C12Y 304/21075 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01);
Abstract
The methods and uses described herein relate to the modulation of the immune system by modulation of Sema3F levels and/or activity, e.g. suppressing allograft rejection or inflammation by administering a Sema3F agonist or increasing an immune response by administering a Sema3F inhibitor.