Location History:
- Baltimore, MD (US) (2012)
- Lutherville, MD (US) (2021)
Company Filing History:
Years Active: 2012-2021
Title: Innovations by David Lee Thomas
Introduction
David Lee Thomas is a notable inventor based in Lutherville, MD (US). He has made significant contributions to the field of antiviral research, particularly in the development of therapeutic methods for treating viral infections. With a total of 2 patents, his work has the potential to impact the lives of many individuals affected by HIV and hepatitis C.
Latest Patents
One of his latest patents focuses on antiviral proteins and their uses in therapeutic methods. This invention describes three proteins, BCL-G (BCL2L14), CMPK2, and LAMP3, which have been discovered to independently restrict HIV-1 replication both in-vivo and in-vitro. The methods outlined in this patent involve administering an effective amount of a pharmaceutical composition comprising these proteins to treat or prevent HIV.
Another significant patent by Thomas involves the use of consensus sequences as vaccine antigens to enhance recognition of virulent viral variants. This invention provides consensus sequences for hepatitis C virus 1a and 1b, along with non-synonymous changes for each residue of the consensus sequences. These sequences are valuable for developing compositions or vaccines for prophylactic use or for treating individuals infected with HCV. Additionally, the patent outlines methods for reducing the likelihood of a chronic phase of infection in HCV-infected individuals and methods for diagnosing HCV 1a or HCV 1b infections.
Career Highlights
David Lee Thomas is affiliated with Johns Hopkins University, where he continues to engage in groundbreaking research. His work has garnered attention in the scientific community, and he is recognized for his innovative approaches to tackling viral infections.
Collaborations
Throughout his career, Thomas has collaborated with esteemed colleagues, including Stuart Campbell Ray and Andrew L Cox. These partnerships have further enriched his research and contributed to the advancement of antiviral therapies.
Conclusion
David Lee Thomas is a prominent inventor whose work in antiviral research has led to significant advancements in therapeutic methods for HIV and hepatitis C. His contributions are poised to make a lasting impact on public health and the treatment of viral infections.