Company Filing History:
Years Active: 2006-2007
Title: Innovations by David L Narum
Introduction
David L Narum is a notable inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of malaria research through his innovative patents. With a total of three patents to his name, Narum's work focuses on developing compositions and methods that can aid in the diagnosis, prevention, and treatment of malaria.
Latest Patents
One of Narum's latest patents is titled "Anti-plasmodium compositions and methods of use." This invention includes compositions that inhibit the binding of erythrocytes, utilizing a family of erythrocyte binding proteins (EBPs). These EBPs are paralogues of the binding protein EBA-175. The invention encompasses peptides of the paralogues that prevent binding, as well as antibodies specific for each paralogue that also inhibit binding. The methods described in this patent utilize these paralogues, antibodies, and peptide compositions for diagnosing and treating diseases such as malaria.
Another significant patent by Narum is "Synthetic genes for malarial proteins and methods of use." This patent involves synthetic gene sequences encoding erythrocyte binding proteins of malaria pathogens. The synthetic genes are designed to approximate mammalian codon composition, making them useful for incorporation into DNA vaccine vectors or various expression vectors for the production of malaria proteins. These synthetic genes can be modified to avoid post-translational modifications in hosts, and their administration as immunization agents is beneficial for inducing immunity against malaria.
Career Highlights
David L Narum is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this prestigious institution has allowed him to focus on critical research aimed at combating malaria and improving public health.
Collaborations
Some of Narum's coworkers include Kim Lee Sim and Hong Liang. Their collaborative efforts contribute to the advancement of research in malaria and related fields.
Conclusion
David L Narum's innovative patents and research efforts play a crucial role in the fight against malaria. His contributions to the field demonstrate the importance of scientific innovation in addressing global health challenges.