This inventor holds 6 USPTO granted patents and 1 published patent application. Top assignees: Yeda Research and Develpment & Co. Ltd, Agilent Technologies, Inc., Leland Stanford Junior University. Active years: 1998-2010.
Location History:
- Stanford, CA (US) (1998 - 2000)
- Menlo Park, CA (US) (2000 - 2010)
Company Filing History:

Years Active: 1998-2010
Title: David L Hirschberg: Innovator in Antibody Specificity and Microarray Technology
Introduction
David L Hirschberg is a notable inventor based in Menlo Park, CA. He has made significant contributions to the field of immunology and diagnostics, holding a total of 6 patents. His work focuses on the therapeutic and diagnostic uses of antibody specificity profiles, which have important implications for understanding immune responses.
Latest Patents
One of Hirschberg's latest patents is centered on the therapeutic and diagnostic uses of antibody specificity profiles. This invention provides a method for determining the antibody specificity profile in an individual. The specificity profile reveals the individual's immune response to multiple antigens and/or epitopes of autoantigens, allergens, graft antigens, and more. The antibody specificity profile is determined through the binding of patient samples comprising antibodies to the arrays, which can include various antigens and epitopes. This invention also outlines means and methods for determining antigen or epitope specificity profiles that can be utilized in developing both generic and individualized diagnosis and treatment for immune-related diseases, including autoimmune diseases, allergies, and graft rejection.
Another significant patent involves microarrays with structured and unstructured probes. This invention provides an apparatus and method for determining a signal produced by a microarray device. The apparatus includes an unstructured probe and a structured probe. The unstructured probe binds to a target and produces a first signal that can be compared to a second signal generated by a structured probe. This comparison allows for a more accurate assessment of the intensity of the first signal, enhancing the reliability of the results.
Career Highlights
Throughout his career, David L Hirschberg has worked with prominent companies such as Yeda Research and Development Co. Ltd and Agilent Technologies, Inc. His experience in these organizations has contributed to his expertise in the field of biotechnology and diagnostics.
Collaborations
Hirschberg has collaborated with notable colleagues, including Michal Eisenbach-Schwartz and Orly Spiegler. These partnerships have likely enriched his research and development efforts, leading to innovative solutions in his field.
Conclusion
David L Hirschberg is a distinguished inventor whose work in antibody specificity and microarray technology has the potential to transform diagnostic and therapeutic approaches in immunology. His contributions continue to influence the field and pave the way for advancements in personalized medicine.