Company Filing History:
Years Active: 2001-2014
Title: David James Hakes: Innovator in Glycosylation and Biochemistry
Introduction: David James Hakes, a prominent inventor based in Willow Grove, Pennsylvania, has amassed an impressive portfolio of 24 patents. His work primarily focuses on advanced biochemistry methodologies that enhance the understanding and application of glycosylation in peptide molecules.
Latest Patents: Among his latest inventions are pioneering techniques in glycopegylation methods and proteins/peptides produced by these methods. This invention encompasses innovative methods and compositions for remodeling peptide molecules, which include the ability to add or delete glycosyl groups and incorporate modifying groups to the peptide structure. Additionally, he has developed methods for refolding mammalian glycosyltransferases produced in bacterial cells. This invention details techniques to refold more than one glycosyltransferase simultaneously, demonstrating significant advancements in the processing and application of these vital enzymes, including their mutant forms that exhibit enhanced refolding capabilities.
Career Highlights: David has played crucial roles in various esteemed companies throughout his career. Notably, he has made significant contributions at Neose Technologies, Inc. and Novo Nordisk A/S, where his innovative research has led to the development of several impactful technologies in the field of biochemistry and pharmaceuticals.
Collaborations: Throughout his career, David has worked alongside distinguished colleagues, including David A Zopf and Shawn DeFrees. These collaborations have fostered an environment of innovation and creativity, resulting in the development of cutting-edge methodologies and advancements in the field.
Conclusion: David James Hakes stands out as a leading inventor in the area of glycosylation and enzyme refolding techniques. His extensive patent portfolio and collaborative efforts reflect his dedication to advancing biochemistry and innovation. With continued research and development, he is poised to make further significant contributions to the scientific community.