David H Holman

Title: David H Holman: Innovator in Apoptosis-Signaling Ligands

Introduction

David H Holman, an inventor based in Charleston, SC, has made significant contributions to the field of medicinal science. With one patent to his name, he is recognized for his innovative work focused on treating diseases linked to cell overproliferation. His research aims to advance medical treatments by utilizing novel compounds and gene therapy methods.

Latest Patents

David H Holman holds a patent for "Ceramides and Apoptosis-Signaling Ligand." This invention provides compounds of a specific formula and pharmaceutically acceptable salts. The disclosed compounds have applications in treating or preventing diseases associated with dysfunctional sphingolipid signal transduction and cell overproliferation. Importantly, the invention includes methods for making these compounds and highlights their use in combination with apoptosis-signaling ligands, such as Fas ligand, potentially administered through gene therapy.

Career Highlights

Currently, David Holman is affiliated with the Musc Foundation for Research Development. His role at this research-oriented organization allows him to continue his pioneering work, contributing to the field of biomedical research through innovative solutions aimed at complex health issues.

Collaborations

Throughout his career, Holman has had the opportunity to work with eminent researchers, including Alicja Bielawska and Yusuf A Hannun. These collaborations exemplify the collective effort in advancing research and fostering innovation within the scientific community.

Conclusion

David H Holman stands out as an influential inventor in the area of apoptosis-signaling ligands. His dedication to innovating treatments for serious diseases through his patented work exhibits the potential impact of his research in the medical field. As he continues to collaborate and push the boundaries of science, his contributions remain significant in the ongoing quest for effective therapies.